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Exerc Sci > Volume 21(4); 2012 > Article
Exercise Science 2012;21(4): 455-464. doi: https://doi.org/10.15857/ksep.2012.21.4.455
PGC-1α유전자 다형성과 신체활동 수준에 따른 대학생의 신체구성, 혈압, 심폐체력의 비교
강현식, 조진경, 하창덕, 이신호
성균관대학교
Comparisons of body composition, blood pressure, and cardiorespiratory fitness according to PGC-1a gene polymorphisms and physical activity levels in college students.
ABSTRACT
The purpose of this study was to investigate whether or not the PGC-1a gene polymorphisms and physical activity levels was associated with body composition, blood pressure and cardiorespiratory fitness(CRF) in korean college students. The PGC-1a gene were genotype in 1286 Korean college students by using the Real-Time Quantitative PCR with TaqMan detection chemistry, CRF was measured as the maximum volume of minute oxygen consumption during a graded treadmill testing, Body composition(height, weight, body mass index, percent body fat, waist, WHR) and blood pressure were measured using our standardized protocols. Chi-square analysis was used to test the Hardy-Weinberg equilibrium based on the genotype frequencies of the PGC-1a gene polymorphism in the study population, and its relative frequency were in the Hardy-Weinberg equilibrium. Therefore, it was confirmed that a sample size(n=1286) of the current study represented the total population appropriately in terms of the PGC-1a genotype distribution. On the other hand, body composition, blood pressure and CRF was not significantly different across the PGC-1a genotypes. Also, body composition and blood pressure was not significantly different across the PGC-1a genotypes and physical activity levels. but CRF was significantly different across the PGC-1a genotypes and middle level of physical activity. In conclusion, the current findings suggest that the PGC-1a genotype is not associated with the body composition, blood pressure and CRF in the korean college students. Also, PGC-1a genotype and physical activity levels is not associated with the body composition, blood pressure in the korean college students.
Key words: PGC-1a, Physical activite level, Body composition, Blood pressure, Cardiorespiratory fitness
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