중강도 운동이 1형 알레르기와 우울성향을 지닌 중학생의 Th Cytokines 및 IgE에 미치는 영향 |
오광훈1, 김정수1, 유영춘2 |
1공주대학교 2건양대학교 |
The Effect of Moderate Exercise on Th Cytokines and IgE of Middle School Students with Type 1 Allergic Symptoms and Depressive Tendency. |
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ABSTRACT |
The purpose of this research is to demonstrate the positive effects of moderate exercise on the changes of Th cytokines and IgE of middle school students with type 1 allergic symptoms and depressive tendency. All the subjects had type 1 allergic symptoms, depressive tendency and had a sedentary lifestyle. They were divided into three groups, moderate aerobic exercise group(AEG; n=9), resistance exercise group(REG; n=8) and control group(CG; n=8) for 12 week's training. Immunoglobulin E, Th1(IFN-γ), Th2(IL-4), Treg(TGF-β1) cytokine, CRP in serum and depressive tendency were analysed before and after exercise session. After 12 weeks of exercise session, a self-reported subjective symptom was changed positively in AEG and REG, but CG showed no changes. Serum IgE decreased significantly in AEG(p<.001) and REG(p<.01), but CG increased and IFN-γ increased significantly in AEG(p<.01) and REG(p<.05) but CG showed no differences. IL-4 was not detected and TGF-β1 increased in three groups and had a pos itive correlation with IFN-γ, but showed no specific relationship with this research.
CRP decreased in AEG and REG, increased in CG with no statistical significance. Depressive tendency decreased significantly in AEG(p<.01) and REG(p<.001) compared to CG and had a significant correlation with IgE(p<.05). These results suggest that moderate exercise is effective to reduce allergic symptoms and depressive tendency simultaneously. |
Key words:
Type 1 allergic symptoms, depressive tendency, moderate exercise, Th 1, Th 2, Treg cytokine, IgE |
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