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Exerc Sci > Volume 11(1); 2002 > Article

Exercise Science 2002;11(1): 35-51.

노화와 운동 효과에 대한 항산화, 내분비, 면역학적 접근

임인수

한양대학교

ABSTRACT

Lim, I.S. The Approach of Antioxidant, Endocrine, & Immune System on Exercise & Aging. Exercise Science 11(1): 35-51, 2002. The purpose of this study was to was examine the effects of short or long term- exercise on oxidative stress, endocrine, and immune system in older adult. This study was to investigate the change of oxidative stress(8-hydroxyguanine, MDA, SOD, catalase, vitamin C,E), endocrine (serotonin, dopamin, endorphin, melatonin, GH, catecholamine, testosterone, cortisol), and immune system(WBC, lymphocyte, neutrophils, CD4, CD8, NK-cell, IgA, IgM, IL-2, IFN-γ) on the effects of short or long-term exercise & aging. All subjects were 37 male older adult and 11 middle age adult. The changes of 8-hydroxyguanine, SOD, catalase, GH, testosterone, cortisol, CD4, CD8, NK-cell, IL-2, IFN-γconcentrations on the effects of long-term exercise were significant among groups(control, 3years, and 5years-training). In conclusion, short or long-term exercise induced positive effects on oxidative stress, endocrine, and immune system in the older adult. Therefore, this results suggested that effects of short and long-term exercise has associated with improve health as well as effect of aging delay.

Key words: aging, antioxidant, endocrine, immune syste