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Exerc Sci > Volume 12(4); 2003 > Article

Exercise Science 2003;12(4): 621-630.

고강도 운동이 싸이토카인과 카테콜라민 농도에 미치는 영향

정덕조¹, 권소양²

¹서원대학교
²서울대학교

ABSTRACT

Chung, D.J., Kwon, S.Y. Effect of a bout of strenuous exercise on cytokine and catecholamine levels in blood. Exercise Science, 12(4): 621-630, 2003. The purpose of the study was to investigate how 85%O2max intense exercise influenced interleukin-2 (IL-2), interleukin-6 (IL-6) cytokine level in blood and whether profile of IL-2, IL-6 cytokine was related to profile of catecholamine. Seven untrained young male ran on treadmills for long time as calory consumption was 400kcal at 85% maximal oxygen consumption(O2max). Blood was collected at rest, after exercise and at recovery 90minutes. Plasma was analyzed for IL-2, IL-6, catecholamines. IL-2 was no significant difference after exercise and at recovery 90 minutes(p>.05), but IL-6 rose significantly after exercise and was going back toward resting level at recovery 90 minutes. Epinephrine significantly increased after exercise(p<.05). Norepinephrine rose significantly after exercise(p<.05) and norepinephrine level at recovery 90 minutes decreased significantly compared to that of after exercise(p<.05). Correlation coefficient between IL-2 and epinephrine was 0.263(p>.05), and that between IL-2 and norepinephrine was 0.239(p>.05). A significant correlations between IL-6 and epinephrine, and IL-6 and norepinephrine were found(r : 0.685, 0.625, respectively, p<.01, p<.05 respectively), In conclusion, a bout of strenous exercise induced increase of IL-6 level, but influenced IL-2 level neither after exercise nor recovery 90 minutes. IL-6 is considerd to cause exercise-induced inflammation response in muscle. And such IL-6 response is influenced by catecholamine or related to physiological condition concerned with catecholamine mechanism.

Key words: strenous exercsise. interleukin-2, interleukin-6, epinephrine, norepinephrine.