|
Exercise Science 2002;11(2): 525-534. |
소뇌의 운동학습 모델에 관한 연구 |
임재형 |
한국과학기술원 |
|
|
|
|
|
|
ABSTRACT |
Im, J. H. A new experimental model for automated motor learning of the cerebellum. Exercise Science, 11(2): 525-534, 2002. The cerebellum is known to operate as an error detector in voluntary movement, particularly in smooth and slow movement. But the possible role of the cerebellum in learning the skills for automated movement has not been tested. I will address this issue by comparing trained and untrained rats for automated movement in the efficacy of the parallel fiber-Purkinje cell synapse. Prior to any study of it, it is necessary to develop a motor learning protocol that help the Purkinje cells of cerebellum engram automated movement better. The subjects were 4-week-old male Sprague-Dawley rats. Training (jump induced by classical conditioning) consisted of 50-trail sessions a day for 25 days. Each trail was composed of a 5s CS(7.5W), followed by a 5s US(scrambled electric foot shock of 0.1mA) and an inter-trial interval of 30s. Task success percentage began to increase in a day and remained stable to the 7th day. Thereafter it was little changed until the end of the 25th day. It was also not significantly different at the 25th day. These results suggest that the trained rats can show long-term retention of the jump motor learning achieved during about 7 days training, and the jump training model may be useful for studying automated motor learning of the cerebellum. |
Key words:
automated motor learning, cerebellum, classical conditioning, engram |
|
|
|