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Exerc Sci > Volume 31(2); 2022 > Article
Exercise Science 2022;31(2): 168-172.
Creatine Kinase and Lactate Dehydrogenase Enzymes Response to Lactate Tolerance Exercise Test
Karamatollah Rahmanian1 , Farhang Hooshmand1 , Masihollah Shakeri2 , Vahid Rahmanian1 , Fatemeh Sotoodeh Jahromi2 , Abdolreza Sotoodeh Jahromi2
1Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran
2Research Center for Noncommunicable Diseases, Jahrom University of Medical Science; Jahrom, Iran
Correspondence  Abdolreza Sotoodeh Jahromi , Tel: +98-71-5434-1501, Fax: +98-71-5434-1509, Email: sotoodehj2002@yahoo.com
Received: December 16, 2021;  Accepted: March 29, 2022.  Published online: May 2, 2022.
ABSTRACT
PURPOSE:
This study aimed to assess alterations in serum creatine kinase (CK) and lactate dehydrogenase (LDH) levels after performing a lactate tolerance exercise test (LTET) in elite male swimmers.
METHODS:
Fourteen male adolescent swimmers participated in this study. All subjects performed LTET (8×100-meter swimming) with a 1-minute recovery interval between eight trainings. Plasma CK and LDH (markers of muscle damage) levels were measured 30 minute before and 24 hours after the test. A paired t-test was used for statistical analysis of data.
RESULTS:
Plasma CK and LDH levels increased immediately after LTET as compared to the values 30 minutes prior to exercise (188.91±34.04 vs. 148.83±29.63 mg/dL, p=.029; 318.17±53.89 vs. 272.08±52.93 mg/dL, p=.010, respectively). Both CK and LDH levels displayed a decreasing trend 24 hours post-LTET; however, there was no significant difference immediately after the test.
CONCLUSIONS:
Plasma CK and LDH levels increased following LTET, which is representative of muscle damage.
Key words: Lactate dehydrogenase enzymes, Muscle damage, Swimmer, Exercise
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