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Exerc Sci > Volume 22(4); 2013 > Article
Exercise Science 2013;22(4): 329-341. doi: https://doi.org/10.15857/ksep.2013.22.4.329
중강도 운동이 1형 알레르기와 우울성향을 지닌 중학생의 Th Cytokines 및 IgE에 미치는 영향
오광훈1, 김정수1, 유영춘2
1공주대학교
2건양대학교
The Effect of Moderate Exercise on Th Cytokines and IgE of Middle School Students with Type 1 Allergic Symptoms and Depressive Tendency.
ABSTRACT
The purpose of this research is to demonstrate the positive effects of moderate exercise on the changes of Th cytokines and IgE of middle school students with type 1 allergic symptoms and depressive tendency. All the subjects had type 1 allergic symptoms, depressive tendency and had a sedentary lifestyle. They were divided into three groups, moderate aerobic exercise group(AEG; n=9), resistance exercise group(REG; n=8) and control group(CG; n=8) for 12 week's training. Immunoglobulin E, Th1(IFN-γ), Th2(IL-4), Treg(TGF-β1) cytokine, CRP in serum and depressive tendency were analysed before and after exercise session. After 12 weeks of exercise session, a self-reported subjective symptom was changed positively in AEG and REG, but CG showed no changes. Serum IgE decreased significantly in AEG(p<.001) and REG(p<.01), but CG increased and IFN-γ increased significantly in AEG(p<.01) and REG(p<.05) but CG showed no differences. IL-4 was not detected and TGF-β1 increased in three groups and had a pos itive correlation with IFN-γ, but showed no specific relationship with this research. CRP decreased in AEG and REG, increased in CG with no statistical significance. Depressive tendency decreased significantly in AEG(p<.01) and REG(p<.001) compared to CG and had a significant correlation with IgE(p<.05). These results suggest that moderate exercise is effective to reduce allergic symptoms and depressive tendency simultaneously.
Key words: Type 1 allergic symptoms, depressive tendency, moderate exercise, Th 1, Th 2, Treg cytokine, IgE
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