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Exerc Sci > Volume 18(3); 2009 > Article
Exercise Science 2009;18(3): 307-316. doi: https://doi.org/10.15857/ksep.2009.18.3.307
노인여성에서 심폐기능과 혈관 경직도의 상관관계
윤은선, 정수진, 제세영
서울시립대학교
Association between cardiorespiratory fitness and arterial stiffness in older women.
ABSTRACT
Aging has a negative effect on large elastic artery structure and function which increases the risk of cardiovascular disease. Pulse wave velocity, an index of arterial stiffness, is associated with high risk of cardiovascular disease. Although some studies suggested that high cardiorespiratory fitness (CRF) levels are associated with enhanced arterial function in older men, little is known that association between CRF and arterial stiffness in older women. We tested the hypothesis that higher levels of CRF are inversely associated with arterial stiffness in a cross sectional study of 28 older women (62 ±3 yrs). Body composition was analyzed using bioelectrical impedance and blood samples were derived after 8 hours overnight fast. Cardiorespiratory fitness was directly measured by maximal exercise treadmill test with expired gas analysis. Arterial stiffness was derived from carotid to femoral pulse wave velocity (PWV). PWV was significantly correlated with age (r=.323, p=.047), systolic blood pressure (r=.682, p=.001), diastolic blood pressure (r=.710, p=.001) and CRF (r=-0.53 p=.002). In multivariable regression models, PWV was associated with diastolic blood pressure and CRF (β=-0.463, p=.046). These results demonstrate that high CRF is associated with arterial stiffness independently of cardiovascular risk factors in older women, which may contribute to lower incidence of cardiovascular disease seen in higher fit older women.
Key words: cardiorespiratory fitness, arterial stiffness, older women
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