Effects of vitamin C & E supplementation on plasma free oxygen radical, total antioxidant capacity, and C-reactive protein after acute aerobic exercise

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doi:2007.16.3.243

Exerc Sci > Volume 16(3); 2007 > Article

Exercise Science 2007;16(3): 243-252. doi: https://doi.org/10.15857/ksep.2007.16.3.243

비타민 C와 E의 복합투여가 일회성 운동 시 혈중 활성 산소 유리기, 총항산화능 및 C-반응성 단백질에 미치는 영향

김정규¹, 신영오², 노성규¹

¹강원대학교
²순천향대학교

Effects of vitamin C & E supplementation on plasma free oxygen radical, total antioxidant capacity, and C-reactive protein after acute aerobic exercise

ABSTRACT

Kim, J.K., Shin, Y.O., Roh, S.K. Effects of vitamin C & E supplementation on plasma free oxygen radical, total antioxidant capacity, and C-reactive protein after acute aerobic exercise. Exercise Science, 16(3): 243-252, 2007. This study was to investigate the effects of vitamin C & E supplementation on plasma free oxygen radical, total antioxidant capacity, and C-reactive protein after acute aerobic exercise. Fourteen healthy male subjects participated in this study. They are divided into two groups; vitamin group(vitamin C 1000mg/day + vitamin E 400IU/day) and placebo group, and supplemented for 4 weeks. All subjects underwent running exercise on a treadmill at before and after treatment for 30 minutes at a work load corresponding to 80% of HRmax, Blood was sampled from a forearm vein at rest, immediately postexercise, and 30min, 24hr after exercise. These samples were analyzed for free oxygen radical, total antioxidant capacity, and plasma CRP content. There was a significant decrease in free oxygen radical, and significant increase in total antioxidant capacity and plasma CRP content, at immediately postexercise and 30min after exercise. Vitamin C & E supplementation significantly increased total antioxidant capacity and significantly decreased CRP content at resting level. Free oxygen radical, total antioxidant capacity, and plasma CRP content, all of which were recoverd at 24hr after exercise in both groups. These results suggested that vitamin C & E supplementation for 4 weeks significantly reduced oxidative stress and significantly improved antioxidant capacity, and resulted in reduced CRP related with oxidative stress.

Key words: vitamin C, E, free oxygen radical, total antioxidant capacity, CRP, exercise